Description

2-Mercapto-6-{[(4-Methylphenyl)Thio]Methyl}Pyrimidin-4(3H)-One is a specialized heterocyclic organic compound featuring a pyrimidinone core functionalized with both mercapto and arylthioalkyl groups. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides, herbicides, or fungicides due to its bioactive heterocyclic structure.
• Chemical Biology Probes: Can be utilized in the design of molecular probes for studying biological processes and target identification.
• Ligand Synthesis: Potential use in the preparation of specialized ligands for catalysis or metal complexation.
• Custom Synthesis & Contract Manufacturing: A critical material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-Mercapto-6-{[(4-Methylphenyl)Thio]Methyl}Pyrimidin-4(3H)-One
CAS No.	299937-81-8
Molecular Formula	C12H12N2OS2
Molecular Weight	264.37 g/mol
Synonyms	2-Mercapto-6-[(4-methylphenylthio)methyl]-4(3H)-pyrimidinone; 6-[(4-Methylphenylthio)methyl]-2-mercapto-4(3H)-pyrimidinone; 2-Thiol-6-((p-tolylthio)methyl)pyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 2-mercapto-6-[[(4-methylphenyl)thio]methyl]-; 299937-81-8; p-Tolylthiomethyl mercaptopyrimidinone derivative
EINECS	Contact for details

Quality Control

Our production of 2-Mercapto-6-{[(4-Methylphenyl)Thio]Methyl}Pyrimidin-4(3H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistent high quality and batch-to-batch reproducibility. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere to prevent oxidation and kept away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.