Description

5H-Pyrrolo3,2-Dpyrimidine, 7-Bromo-4-Methoxy-5-(2-Propenyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolopyrimidine core structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted small molecule drugs, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex, biologically active molecules for drug discovery pipelines.
• Kinase Inhibitor Development: Used as a core scaffold for designing and optimizing potent and selective kinase inhibitors.
• Oncological Research: Employed in the construction of candidate compounds targeting various cancer pathways.
• Medicinal Chemistry SAR Studies: Utilized for structure-activity relationship (SAR) exploration to improve drug potency and selectivity.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study specific biological processes.
• Custom Synthesis: A fundamental building block for contract research organizations (CROs) and CDMOs performing bespoke organic synthesis.

Basic Information

Product Name	5H-Pyrrolo3,2-Dpyrimidine, 7-Bromo-4-Methoxy-5-(2-Propenyl)-
CAS No.	299916-86-2
Molecular Formula	C10H10BrN3O
Molecular Weight	268.11 g/mol
Synonyms	7-Bromo-4-methoxy-5-(prop-2-en-1-yl)-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidine, 7-bromo-4-methoxy-5-(2-propenyl)-; 7-Bromo-4-methoxy-5-(allyl)-5H-pyrrolo[3,2-d]pyrimidine; 5-Allyl-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine; CAS 299916-86-2; 7-Bromo-4-methoxy-5-allyl-5H-pyrrolo[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 5H-Pyrrolo3,2-Dpyrimidine, 7-Bromo-4-Methoxy-5-(2-Propenyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.