Description

5H-Pyrrolo3,2-Dpyrimidine, 7-Bromo-4-(Phenylmethoxy)-5-2-(Trimethylsilyl)Ethoxymethyl- is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds to develop novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical synthesis facilities engaged in creating complex, target-specific molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for creating molecular probes and tool compounds to study enzyme function and cellular processes.
• Material Science: Potential building block for organic electronic materials and advanced polymers due to its conjugated pyrrolopyrimidine structure.
• Custom Synthesis & Contract Manufacturing: An essential starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	5H-Pyrrolo3,2-Dpyrimidine, 7-Bromo-4-(Phenylmethoxy)-5-2-(Trimethylsilyl)Ethoxymethyl-
CAS No.	299916-85-1
Molecular Formula	C19H25BrN2O2Si
Molecular Weight	421.41 g/mol
Synonyms	7-Bromo-4-(benzyloxy)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-d]pyrimidine; 4-(Benzyloxy)-7-bromo-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-d]pyrimidine; 5-((2-(Trimethylsilyl)ethoxy)methyl)-7-bromo-4-(phenylmethoxy)-5H-pyrrolo[3,2-d]pyrimidine; 7-Bromo-4-(phenylmethoxy)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-d]pyrimidine; TMS-Protected Pyrrolopyrimidine Bromide; BEMP-Br (common abbreviation in medicinal chemistry)
EINECS	Contact for details

Quality Control

Our 5H-Pyrrolo3,2-Dpyrimidine derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider using an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.