Description

4-Amino-2-Phenyl-6-(Trifluoromethyl)Pyrimidine-5-Carbonitrile is a high-value, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl-substituted pyrimidine core offers significant advantages in modulating the physicochemical properties of target molecules, making it indispensable for research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced materials scientists for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials, including OLEDs and semiconductors, due to its electron-deficient pyrimidine ring.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing for clients.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	4-Amino-2-Phenyl-6-(Trifluoromethyl)Pyrimidine-5-Carbonitrile
CAS No.	297149-21-4
Molecular Formula	C12H7F3N4
Molecular Weight	264.21 g/mol
Synonyms	4-Amino-2-phenyl-6-(trifluoromethyl)pyrimidine-5-carbonitrile; 2-Phenyl-4-amino-6-trifluoromethylpyrimidine-5-carbonitrile; 6-(Trifluoromethyl)-4-amino-2-phenylpyrimidine-5-carbonitrile; 4-Amino-2-phenyl-6-(trifluoromethyl)-5-pyrimidinecarbonitrile; 5-Cyano-4-amino-2-phenyl-6-(trifluoromethyl)pyrimidine; 297149-21-4; 4-Amino-2-phenyl-6-trifluoromethyl-5-cyanopyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-2-Phenyl-6-(Trifluoromethyl)Pyrimidine-5-Carbonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and MS analysis. Our quality commitment ensures the material meets the high standards required for GMP-grade intermediates and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.