Description

Fmoc-Aminomalonic Acid CAS NO 296261-32-0 is a specialized, high-purity amino acid derivative protected with a fluorenylmethyloxycarbonyl (Fmoc) group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of unique structural elements into peptide chains. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-fidelity, custom peptide sequences for drug discovery, diagnostic development, and biochemical research.

Application

• Key intermediate in solid-phase peptide synthesis (SPPS) for research and production.
• Building block for incorporating unnatural amino acids and complex molecular architectures into peptides.
• Precursor in the development of peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Used in the synthesis of peptidomimetics and constrained peptides for drug discovery programs.
• Essential reagent for combinatorial chemistry libraries focused on bioactive peptides.
• Research chemical for studying enzyme mechanisms and bioconjugation techniques.
• Starting material for the synthesis of fluorescent probes and molecular tags.

Basic Information

Product Name	Fmoc-Aminomalonic Acid
CAS No.	296261-32-0
Molecular Formula	C₁₈H₁₅NO₆
Molecular Weight	341.31 g/mol
Synonyms	Fmoc-Aminomalonic acid; 2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]propanedioic acid; N-Fmoc-aminomalonic acid; N-[(9-Fluorenylmethoxy)carbonyl]aminomalonic acid; Fmoc-NH-CH(COOH)₂; Fmoc-Ama-OH; (2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)malonic acid)
EINECS	Contact for details

Quality Control

Our Fmoc-Aminomalonic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.