Description

Imidazo[1,2-A]Pyrimidin-2(3H)-One, 1,5-Dihydro-5-Thioxo-7-(Trifluoromethyl)- is a high-value heterocyclic building block distinguished by its unique fused ring system and trifluoromethyl group. This compound matters for its role as a critical intermediate in the synthesis of novel pharmaceuticals and agrochemicals, where it imparts desirable metabolic stability and bioavailability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors for creating new active ingredients.

Application

• Pharmaceutical Intermediate: Key scaffold for the development of new drug candidates, particularly in antiviral, anticancer, and CNS-targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thioxo and trifluoromethyl motifs.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential building block for advanced organic electronic materials due to its conjugated π-system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and library production.

Basic Information

Product Name	Imidazo[1,2-A]Pyrimidin-2(3H)-One, 1,5-Dihydro-5-Thioxo-7-(Trifluoromethyl)-
CAS No.	294880-84-5
Molecular Formula	C7H4F3N3OS
Molecular Weight	235.19 g/mol
Synonyms	7-(Trifluoromethyl)-1,5-dihydro-5-thioxoimidazo[1,2-a]pyrimidin-2(3H)-one; 1,5-Dihydro-5-thioxo-7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-2(3H)-one; 7-Trifluoromethyl-1,5-dihydro-5-thioxoimidazo[1,2-a]pyrimidin-2(3H)-one; Imidazo[1,2-a]pyrimidine-2(3H)-one, 1,5-dihydro-5-thioxo-7-(trifluoromethyl)-; 294880-84-5; 7-(Trifluoromethyl)-5-thioxo-3,5-dihydro-2H-imidazo[1,2-a]pyrimidin-2-one
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyrimidin-2(3H)-One, 1,5-Dihydro-5-Thioxo-7-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.