Description

Des-Gln14-Ghrelin (Rat) is a specific, modified peptide fragment of the appetite-regulating hormone ghrelin. This compound is a critical research tool for studying the structure-activity relationships and metabolic signaling pathways of ghrelin in rodent models. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, obesity, and metabolic disorder research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the ghrelin receptor (GHSR-1a) signaling and its role in appetite stimulation and growth hormone secretion.
• Pharmacology Studies: Essential for in vitro and in vivo assays to evaluate the potency and efficacy of novel ghrelin analogs or receptor antagonists.
• Metabolic Pathway Analysis: Employed to dissect the specific contributions of different ghrelin peptide regions to its biological functions in rat models.
• Drug Discovery & Development: Serves as a key intermediate or comparator in the development of therapeutic agents targeting metabolic syndromes and cachexia.
• Academic & Institutional Research: Supports fundamental research in universities and institutes focused on neuroendocrinology and energy homeostasis.

Basic Information

Product Name	Des-Gln14-Ghrelin (Rat)
CAS No.	293735-04-3
Molecular Formula	C147H246N44O42
Molecular Weight	3277.8 g/mol
Synonyms	Des-Gln14-Ghrelin; Ghrelin (rat) fragment 1-13; n-Octanoyl-Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-NH2; Rat Des-Gln(14)-Ghrelin; Acylated Ghrelin (1-13) (Rat); GHRP (Rat 1-13); Growth Hormone Secretagogue Peptide Fragment
EINECS	Contact for details

Quality Control

Our Des-Gln14-Ghrelin (Rat) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.