Description

Isopropyl 4-(2,4-Dichlorophenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is a critical building block in the synthesis of active pharmaceutical ingredients (APIs), valued for its role in constructing specific pharmacophores. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of dihydropyrimidinone (DHPM) based APIs, which are a class of compounds with diverse biological activities.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for developing new drug candidates targeting various diseases.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, or insecticides, leveraging its dichlorophenyl and tetrahydropyrimidine motifs.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme mechanisms or biological pathways in academic and industrial R&D.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	Isopropyl 4-(2,4-Dichlorophenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	292853-08-8
Molecular Formula	C16H18Cl2N2O3
Molecular Weight	357.23 g/mol
Synonyms	Isopropyl 4-(2,4-dichlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carboxyisopropyl 4-(2,4-dichlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine; 4-(2,4-Dichlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid isopropyl ester; DHPM derivative; Biginelli reaction product; CAS 292853-08-8
EINECS	Contact for details

Quality Control

Our Isopropyl 4-(2,4-Dichlorophenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.