Description

2,3,4,6-Tetrafluorobenzyl Chloride is a versatile and highly reactive organofluorine building block, essential for introducing the tetrafluorobenzyl moiety into complex molecular architectures. Its primary value lies in enabling the synthesis of advanced intermediates for pharmaceuticals and agrochemicals, where the fluorine atoms impart desirable properties like metabolic stability and enhanced bioavailability. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and CNS-targeted drug candidates.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine pattern enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Chemistry: Employed to introduce fluorinated benzyl groups into polymers, modifying surface properties, chemical resistance, and thermal characteristics.
• Organic Synthesis Reagent: A crucial reagent for nucleophilic substitution reactions, facilitating the alkylation of amines, alcohols, and carboxylic acids to create complex fluorinated molecules.
• Material Science Research: Used in developing novel fluorinated organic compounds for electronic materials, coatings, and advanced functional materials.

Basic Information

Product Name	2,3,4,6-Tetrafluorobenzyl Chloride
CAS No.	292621-61-5
Molecular Formula	C7H3ClF4
Molecular Weight	198.55 g/mol
Synonyms	(2,3,4,6-Tetrafluorophenyl)methyl Chloride; α-Chloro-2,3,4,6-tetrafluorotoluene; 2,3,4,6-Tetrafluorobenzylchloride; Benzene, 1-(chloromethyl)-2,3,4,6-tetrafluoro-; 1-(Chloromethyl)-2,3,4,6-tetrafluorobenzene; Tetrafluorobenzyl Chloride (mixed isomer reference); TFBC
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetrafluorobenzyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.