Description

3-Chloro-2,4,5,6-Tetrafluorobenzylchloride is a highly functionalized benzyl halide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of chlorine and fluorine atoms, which enable precise molecular modifications for creating compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a multi-halogenated benzyl moiety.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in display technologies.
• Polymer Modification: Employed to introduce halogenated benzyl groups into polymer chains, altering thermal and chemical resistance properties.
• Organic Electronics: Acts as a precursor for materials used in organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki and Buchwald-Hartwig couplings for constructing complex biaryl systems.

Basic Information

Item	Details
Product Name	3-Chloro-2,4,5,6-Tetrafluorobenzylchloride
CAS No.	292621-59-1
Molecular Formula	C7H2Cl2F4
Molecular Weight	244.99 g/mol
Synonyms	1-(Chloromethyl)-3-chloro-2,4,5,6-tetrafluorobenzene; 2,4,5,6-Tetrafluoro-3-chlorobenzyl Chloride; α,3-Dichloro-2,4,5,6-tetrafluorotoluene; Benzene, 1-(chloromethyl)-3-chloro-2,4,5,6-tetrafluoro-; 3-Chloro-2,4,5,6-tetrafluorobenzyl chloride; Tetrafluorobenzylchloride derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4,5,6-Tetrafluorobenzylchloride is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.