Description

3,4-Difluoro-2-Nitroaniline is a high-purity aromatic amine derivative characterized by its difluoro and nitro substituents, which impart unique reactivity and electronic properties. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those containing fluorinated aniline moieties for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and pigments, where the nitro and amino groups facilitate chromophore formation.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and reduction reactions to create more complex fluorinated aromatic systems.

Basic Information

Product Name	3,4-Difluoro-2-Nitroaniline
CAS No.	292145-76-7
Molecular Formula	C6H4F2N2O2
Molecular Weight	174.11 g/mol
Synonyms	2-Nitro-3,4-difluoroaniline; 3,4-Difluoro-2-nitrobenzenamine; 2-Amino-3,4-difluoronitrobenzene; 3,4-Difluoro-2-nitro-phenylamine; Benzenamine, 3,4-difluoro-2-nitro-; 292145-76-7; 3,4-DFNA
EINECS	Contact for details

Quality Control

Every batch of 3,4-Difluoro-2-Nitroaniline is manufactured under a cGMP-compliant quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets stringent internal specifications, with purity typically exceeding 98.0% (HPLC). A comprehensive Certificate of Analysis (COA) detailing assay, related substances, residual solvents, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.