Description

Ac-D-2-Nal-4-Chloro-D-Phe-β-(3-Pyridyl)-D-Ala-Gly-Arg-Pro-D-Ala-Nh2 is a synthetic, non-natural peptide sequence designed for advanced biochemical research and therapeutic development. This compound is engineered to exhibit high receptor binding affinity and metabolic stability, making it a critical tool for studying peptide-protein interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, metabolic disorders, and targeted drug delivery systems.

Application

• Biochemical Research: Used as a reference standard or active probe in receptor binding assays, enzyme inhibition studies, and cellular signaling pathway analysis.
• Drug Discovery: Serves as a lead compound or molecular scaffold for the development of novel peptide-based therapeutics, particularly in oncology.
• Pharmacology Studies: Employed in in vitro and in vivo models to evaluate pharmacokinetics, biodistribution, and therapeutic efficacy.
• Diagnostic Development: Potential use in the design of targeted imaging agents or diagnostic probes due to its specific binding characteristics.
• Academic Research: A key reagent for fundamental studies in peptide chemistry, structural biology, and molecular pharmacology.

Basic Information

Product Name	Ac-D-2-Nal-4-Chloro-D-Phe-β-(3-Pyridyl)-D-Ala-Gly-Arg-Pro-D-Ala-Nh2
CAS No.	292141-31-2
Molecular Formula	C58H70ClN13O10
Molecular Weight	1144.7 g/mol (theoretical)
Synonyms	Ac-D-2-Nal-4-Cl-D-Phe-β-(3-Pyridyl)-D-Ala-Gly-Arg-Pro-D-Ala-amide; [Ac-D-2-Nal1,4-Cl-D-Phe2,D-Ala3,Arg6,D-Ala8]-Peptide; 292141-31-2; Custom Melanocortin Receptor Ligand; MC4R Peptide Analog; β-(3-Pyridyl)-Alanine Containing Peptide; N-Acetylated Peptide Amide; Research Peptide 292141-31-2
EINECS	Contact for details

Quality Control

Every batch of our high-purity peptides is manufactured under strict cGMP-like conditions and undergoes comprehensive analytical characterization. Quality is assured through multiple orthogonal methods including HPLC, MS, and amino acid analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and content is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95% (Area percent at 214 nm)
Assay (Peptide Content)	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.