Description

2-Chloro-4-Methyl-Thiazole-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, enabling the efficient introduction of both the thiazole heterocycle and a sulfonyl chloride group for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Chemical Research & Development: A versatile reagent for constructing complex heterocyclic systems and for sulfonamide coupling reactions in medicinal chemistry.
• Material Science: Potential building block for creating functional polymers or ligands with specific electronic or binding properties.
• Dye and Pigment Industry: Intermediate for synthesizing specialized dyes and pigments containing sulfur heterocycles.

Basic Information

Product Name	2-Chloro-4-Methyl-Thiazole-5-Sulfonyl Chloride
CAS No.	292138-59-1
Molecular Formula	C4H3Cl2NO2S2
Molecular Weight	240.11 g/mol
Synonyms	5-(Chlorosulfonyl)-2-chloro-4-methylthiazole; 2-Chloro-4-methyl-1,3-thiazole-5-sulfonyl chloride; 4-Methyl-2-chlorothiazole-5-sulfonyl chloride; 2-Chloro-4-methylthiazole-5-sulfonyl chloride; Thiazole-5-sulfonyl chloride, 2-chloro-4-methyl-; 292138-59-1; 2-Chloro-4-methyl-δ²-thiazoline-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methyl-Thiazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.