Description

n-ω-Hydroxyl-Nor-L-Arginine, Dihydrochloride is a high-purity, chemically modified derivative of the amino acid L-arginine, specifically designed for advanced research and pharmaceutical development. This compound serves as a critical building block and a potent, selective inhibitor of nitric oxide synthase (NOS), enabling precise biochemical pathway modulation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors focused on cardiovascular, neurological, and inflammatory disease research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents targeting nitric oxide pathways.
• Biochemical Research: Used as a selective inhibitor in enzymatic studies to investigate the role of nitric oxide synthase (NOS) isoforms.
• Proteomics & Peptide Synthesis: Serves as a specialized, modified amino acid for constructing custom peptides with enhanced stability or specific biological activity.
• Cell Culture & In Vitro Studies: Applied in research models to study the effects of NOS inhibition on cell signaling, proliferation, and apoptosis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Drug Discovery Screening: Employed in high-throughput screening assays to identify and validate new drug candidates affecting vascular and neural systems.

Basic Information

Product Name	n-ω-Hydroxyl-Nor-L-Arginine, Dihydrochloride
CAS No.	291758-32-2
Molecular Formula	C6H16Cl2N4O3
Molecular Weight	263.12 g/mol
Synonyms	Nω-Hydroxy-nor-L-arginine dihydrochloride; ω-Hydroxy-nor-L-arginine dihydrochloride; Nor-NOHA dihydrochloride; N5-(Hydroxyamino)-L-norornithine dihydrochloride; L-Nor-Nω-hydroxyarginine dihydrochloride; H-Nor-Arg(NOH)-OH·2HCl; NOS Inhibitor; (2S)-2-Amino-5-[(hydroxyamino)amino]pentanoic acid dihydrochloride
EINECS	Contact for details

Quality Control

Our n-ω-Hydroxyl-Nor-L-Arginine, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.