Description

n-Methyl-D-Leucyl-D-Valyl-D-Phenylalanyl-D-Phenylalanyl-D-Leucinamide is a synthetic, high-purity peptide derivative designed for advanced research and development applications. This compound is valued for its specific stereochemistry and sequence, making it a critical building block in peptide science and medicinal chemistry. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in the development of novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate, inhibitor, or model compound in enzymatic studies, receptor binding assays, and structure-activity relationship (SAR) investigations.
• Medicinal Chemistry: Acts as a crucial scaffold for designing and optimizing peptide mimetics with enhanced stability, bioavailability, and target specificity.
• Proteomics & Peptide Libraries: Incorporated into custom peptide libraries for high-throughput screening to identify new biological leads and therapeutic targets.
• Academic Research: Employed in university and institutional labs for fundamental studies in peptide synthesis, folding, and molecular recognition processes.
• Contract Research Organizations (CROs): Utilized by CROs providing specialized synthesis and testing services to the biopharma industry.

Basic Information

Product Name	n-Methyl-D-Leucyl-D-Valyl-D-Phenylalanyl-D-Phenylalanyl-D-Leucinamide
CAS No.	290828-45-4
Molecular Formula	C46H64N6O6
Molecular Weight	797.04 g/mol
Synonyms	N-Methyl-D-leucyl-D-valyl-D-phenylalanyl-D-phenylalanyl-D-leucinamide; D-Leu-N-Me-D-Val-D-Phe-D-Phe-D-Leu-NH2; (D-Leu-N-Me-D-Val-D-Phe-D-Phe-D-Leu-NH2); H-D-Leu-N-Me-D-Val-D-Phe-D-Phe-D-Leu-NH2; All-D-Pentapeptide Amide N-Methylated; N-Methylated D-Configuration Pentapeptide; 290828-45-4; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our n-Methyl-D-Leucyl-D-Valyl-D-Phenylalanyl-D-Phenylalanyl-D-Leucinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to verify stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity (HPLC)	≥ 99.0% D-isomer for each residue

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.