Description

4-Fluoro-5-Hydroxy-2-Methylindole is a high-purity, fluorinated indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its unique molecular scaffold, which combines a reactive hydroxyl group with a fluorine substituent, enabling precise structural modifications in complex molecule synthesis. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Development: Used in creating advanced pesticides and herbicides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in electronic materials and organic light-emitting diodes (OLEDs).
• Biochemical Probe Synthesis: Employed in the design and manufacture of labeled compounds and probes for biochemical and diagnostic applications.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	4-Fluoro-5-Hydroxy-2-Methylindole
CAS No.	288385-88-6
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	5-Hydroxy-4-fluoro-2-methylindole; 2-Methyl-4-fluoro-5-hydroxyindole; 4-Fluoro-5-hydroxy-2-methyl-1H-indole; 1H-Indol-5-ol, 4-fluoro-2-methyl-; 288385-88-6; 4-Fluoro-5-hydroxy-2-methylindole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Hydroxy-2-Methylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.