Description

3-Amino-4-Methoxybenzene-1-Sulfonyl Chloride is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its reactive sulfonyl chloride group and protected amine functionality make it a versatile intermediate for constructing complex molecules with high precision. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides that require specific sulfonamide linkages.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing azo dyes and other colorants where amino and sulfonyl groups modify hue and fastness properties.
• Polymer Chemistry: Employed in the creation of specialty polymers and functional materials, such as sulfonated polymers for ion-exchange membranes.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on heterocyclic chemistry and medicinal chemistry.
• Custom Synthesis: Serves as a starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Item	Details
Product Name	3-Amino-4-Methoxybenzene-1-Sulfonyl Chloride
CAS No.	288158-29-2
Molecular Formula	C7H8ClNO3S
Molecular Weight	221.66 g/mol
Synonyms	2-Amino-5-Methoxybenzenesulfonyl Chloride; 5-Methoxy-2-aminobenzenesulfonyl Chloride; 3-Amino-4-methoxybenzenesulfonyl chloride; 2-Amino-5-methoxybenzene-1-sulfonyl chloride; 5-Methoxy-2-aminobenzene-1-sulfonyl chloride; 3-Amino-4-methoxy-1-benzenesulfonyl chloride; 2-Aminoanisole-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-Amino-4-Methoxybenzene-1-Sulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting customer specifications. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed parameters. Our quality system is designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.