Description

4-Amino-2-(4-Methylphenyl)-6-(Methylthio)Pyrimidine-5-Carbonitrile is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the creation of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Serves as a scaffold for designing molecular probes and enzyme inhibitors in biochemical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-Amino-2-(4-Methylphenyl)-6-(Methylthio)Pyrimidine-5-Carbonitrile
CAS No.	287922-40-1
Molecular Formula	C13H12N4S
Molecular Weight	256.33 g/mol
Synonyms	4-Amino-2-p-tolyl-6-(methylthio)pyrimidine-5-carbonitrile; 2-(4-Methylphenyl)-4-amino-6-(methylthio)-5-pyrimidinecarbonitrile; 6-(Methylthio)-4-amino-2-(4-methylphenyl)pyrimidine-5-carbonitrile; 4-Amino-2-(4-methylphenyl)-6-(methylsulfanyl)pyrimidine-5-carbonitrile; 4-Amino-6-(methylthio)-2-(4-methylphenyl)pyrimidine-5-carbonitrile; CAS 287922-40-1
EINECS	Contact for details

Quality Control

Our 4-Amino-2-(4-Methylphenyl)-6-(Methylthio)Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to minimize moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.