Description

H-Cys(Farnesyl)-Val-Ile-Ser-Oh is a specialized farnesylated peptide derivative, a key intermediate in the synthesis of biologically active compounds. Its value lies in its role as a precise building block for advanced research and development in targeted therapeutic areas. This high-purity peptide is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on signal transduction, oncology, and metabolic disease pathways.

Application

• Pharmaceutical Research & Development: Critical intermediate in the synthesis of prenylated protein analogs and inhibitors for studying Ras-related oncogenic pathways.
• Chemical Biology Probes: Used to create labeled or modified peptides for investigating protein farnesylation and intracellular trafficking mechanisms.
• Enzyme Substrate Studies: Serves as a specific substrate for farnesyltransferase assays and enzyme kinetics research.
• Lead Compound Optimization: Employed in medicinal chemistry for structure-activity relationship (SAR) studies to develop novel therapeutic candidates.
• Academic Research: Utilized in university and institutional labs for fundamental studies in cell signaling, post-translational modifications, and cancer biology.
• Bioconjugation: Acts as a starting material for the synthesis of peptide-drug conjugates or other bioconjugates due to its reactive thiol group.

Basic Information

Product Name	H-Cys(Farnesyl)-Val-Ile-Ser-Oh
CAS No.	287918-93-8
Molecular Formula	C33H57N5O5S
Molecular Weight	635.90 g/mol
Synonyms	Farnesyl-Cys-Val-Ile-Ser-OH; S-[(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl]-L-cysteinyl-L-valyl-L-isoleucyl-L-serine; L-Cysteine, S-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-, 1-[(1S)-1-[[(1S)-2-hydroxy-1-(1-hydroxyethyl)propyl]amino]-2-methyl-1-oxobutyl]-2-(1-methylethyl)-1,2-ethanediyl ester; Cys(Farnesyl)-Val-Ile-Ser; Prenylated CVIS peptide; Farnesylated tetrapeptide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. Each batch is characterized by advanced analytical techniques including HPLC, MS, and NMR to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.