Description

H-D-Ala-D-Ala-D-Ala-D-Ala-D-Ala-D-Ala-Oh is a synthetic, homochiral hexapeptide composed entirely of D-alanine residues. This unique, all-D-amino acid sequence is a critical building block in advanced peptide research and pharmaceutical development, offering exceptional resistance to enzymatic degradation. It is primarily utilized by research institutions and pharmaceutical companies specializing in novel antimicrobial agents, peptidomimetics, and the study of chiral molecular recognition.

Application

• Antimicrobial Peptide (AMP) Research: Serves as a key structural component or mimic in the development of novel antibiotics targeting bacterial cell wall synthesis.
• Peptidomimetic Drug Design: Acts as a stable, protease-resistant scaffold for creating therapeutic peptides with enhanced bioavailability and metabolic stability.
• Biochemical Tool Compound: Used in enzymatic studies to investigate the specificity and mechanism of peptidases and other enzymes that interact with D-amino acid polymers.
• Chirality Studies: Employed as a model compound in research focused on the biological activity and physical properties of all-D peptides versus their L-configured counterparts.
• Material Science: Investigated for the creation of novel biomaterials and self-assembling nanostructures due to its defined secondary structure potential.

Basic Information

Product Name	H-D-Ala-D-Ala-D-Ala-D-Ala-D-Ala-D-Ala-Oh
CAS No.	286842-36-2
Molecular Formula	C18H32N6O7
Molecular Weight	444.48 g/mol
Synonyms	Hexa-D-alanine; D-Alanine hexamer; H-(D-Ala)6-OH; All-D-hexaalanine; D-Ala-D-Ala-D-Ala-D-Ala-D-Ala-D-Ala; Poly-D-alanine (hexamer); (R)-2-Amino-N-((R)-1-((R)-1-((R)-1-((R)-1-((R)-1-carboxyethylamino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)propanamide
EINECS	Contact for details

Quality Control

Every batch of H-D-Ala-D-Ala-D-Ala-D-Ala-D-Ala-D-Ala-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring compliance with research and development standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.