Description

6-Chloro-2-Fluoro-3-Methylbenzaldehyde is a versatile halogenated benzaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the chloro-fluoro-methyl motif can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers where specific halogen interactions are required.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Methylbenzaldehyde
CAS No.	286474-59-7
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-Fluoro-6-chloro-3-methylbenzaldehyde; 3-Methyl-2-fluoro-6-chlorobenzaldehyde; 6-Chloro-2-fluoro-m-tolualdehyde; Benzaldehyde, 6-chloro-2-fluoro-3-methyl-; 286474-59-7; 2-Fluoro-6-chloro-3-methyl-benzaldehyde
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Methylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.