Description

H-Val-Lys-Lys-Arg-Oh CAS NO 286471-39-4 is a synthetic tetrapeptide sequence composed of Valine (Val), Lysine (Lys), and Arginine (Arg) residues. This peptide is of significant interest in biochemical and pharmaceutical research due to its specific cationic and structural properties derived from the basic amino acids lysine and arginine. It serves as a critical building block and research tool for scientists in peptide synthesis, drug discovery, and proteomics.

Application

• Pharmaceutical Research & Drug Discovery: Used as a key intermediate or a model compound in the development of novel peptide-based therapeutics, including antimicrobial peptides (AMPs) and cell-penetrating peptides (CPPs).
• Biochemical Reagent: Employed in enzymatic studies, substrate specificity assays, and as a standard in mass spectrometry for protein/peptide analysis.
• Cosmeceutical Development: Investigated for potential applications in advanced skincare formulations targeting skin barrier function and delivery.
• Academic & Institutional Research: Serves as a fundamental tool in university and laboratory settings for studying peptide structure-activity relationships (SAR), stability, and conjugation chemistry.
• Diagnostic Kit Manufacturing: Can be utilized in the development and calibration of immunoassays and other diagnostic platforms.

Basic Information

Product Name	H-Val-Lys-Lys-Arg-Oh
CAS No.	286471-39-4
Molecular Formula	C24H48N10O5
Molecular Weight	556.71 g/mol
Synonyms	Val-Lys-Lys-Arg; VKKR Peptide; H-Val-Lys-Lys-Arg-OH; Tetrapeptide VKKR; L-Valyl-L-lysyl-L-lysyl-L-arginine; Argireline Precursor Fragment; Acetyl Hexapeptide-8 Related Peptide; CAS 286471-39-4
EINECS	Contact for details

Quality Control

Our H-Val-Lys-Lys-Arg-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and chiral purity analysis to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant use and storage under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Optical Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.