Description

Fmoc-Met-Oh-1-13C CAS NO 286460-73-9 is a stable isotope-labeled derivative of the amino acid methionine, specifically designed for advanced research and development. This compound is essential for applications requiring precise metabolic tracking and structural elucidation, such as in proteomics and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical companies, and CROs engaged in peptide synthesis, mass spectrometry, and tracer studies.

Application

• Isotope-Labeled Peptide Synthesis: As a building block for synthesizing peptides with carbon-13 labels for NMR and mass spectrometry studies.
• Metabolic Pathway Analysis: Used as a tracer to study methionine metabolism and related biochemical pathways in biological systems.
• Pharmaceutical Research: Critical in the development and quality control of peptide-based drugs and APIs, enabling precise analytical measurements.
• Proteomics & Biomarker Discovery: Facilitates quantitative proteomic analysis through stable isotope labeling techniques (e.g., SILAC).
• Structural Biology: Aids in protein structure determination and dynamics studies using NMR spectroscopy.
• Academic & Industrial R&D: Serves as a key reagent in chemical biology and medicinal chemistry research programs.

Basic Information

Product Name	Fmoc-Met-Oh-1-13C
CAS No.	286460-73-9
Molecular Formula	C₂₁H₂¹³CNO₄S
Molecular Weight	~383.45 g/mol (¹³C)
Synonyms	Fmoc-L-methionine-1-¹³C; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-methionine-1-¹³C; (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-(methylsulfanyl)butanoic-1-¹³C acid; Fmoc-Met-OH-1-¹³C; Fmoc-Met-¹³C; Fmoc-L-Met-1-¹³C; N-Fmoc-L-methionine-1-¹³C; Fmoc-Methionine-1-¹³C
EINECS	Contact for details

Quality Control

Our Fmoc-Met-Oh-1-13C is manufactured under strict quality systems to ensure high isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity (by HPLC), and chiral purity. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (¹³C)	≥ 99 atom %
Optical Rotation	-20.0° to -24.0° (c=1, DMF)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.