Description

H-Tyr-Gly-Arg-Phe-Ser-Oh Hcl is a synthetic peptide sequence with the CAS number 286458-87-5, commonly utilized as a key intermediate in advanced pharmaceutical research and development. This compound matters for its role in the synthesis of complex peptide-based therapeutics and biochemical tools, offering researchers a high-purity building block for creating novel drug candidates. It is primarily needed by biotechnology firms, pharmaceutical R&D laboratories, and academic institutions focused on endocrinology, neuroscience, and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of larger, biologically active peptide hormones and therapeutic agents.
• Biochemical Research: Used in structure-activity relationship (SAR) studies to understand peptide-receptor interactions and optimize drug efficacy.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in peptide manufacturing.
• Proteomics & Peptide Library Synthesis: Employed in the construction of combinatorial peptide libraries for high-throughput screening against biological targets.
• Neuroscience Research: Investigated for potential activity in neurological pathways due to its specific amino acid sequence.

Basic Information

Product Name	H-Tyr-Gly-Arg-Phe-Ser-Oh Hcl
CAS No.	286458-87-5
Molecular Formula	C32H47N11O8 • xHCl
Molecular Weight	Contact for details
Synonyms	Tyr-Gly-Arg-Phe-Ser-OH hydrochloride; YGRFS-OH • HCl; H-Tyr-Gly-Arg-Phe-Ser-OH hydrochloride; L-Tyrosyl-glycyl-L-arginyl-L-phenylalanyl-L-serine hydrochloride; Pentapeptide YGRFS hydrochloride; CAS 286458-87-5; Peptide Sequence 5
EINECS	Contact for details

Quality Control

Our H-Tyr-Gly-Arg-Phe-Ser-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and moisture content, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation. For short-term use, store in a desiccator at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Acetate Content (HPIC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.