Description

4-Chloro-7-Methoxy-6-Benzyloxyquinazoline is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of targeted therapeutic agents, offering precise chemical functionality for complex molecular construction. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors and other targeted cancer therapies.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex quinazoline-based molecular architectures.
• Biochemical Research: Serves as a reference standard or a starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Process Development: Employed in the optimization and scale-up of API (Active Pharmaceutical Ingredient) manufacturing routes.

Basic Information

Product Name	4-Chloro-7-Methoxy-6-Benzyloxyquinazoline
CAS No.	286371-65-1
Molecular Formula	C₁₆H₁₃ClN₂O₂
Molecular Weight	300.74 g/mol
Synonyms	6-(Benzyloxy)-4-chloro-7-methoxyquinazoline; 4-Chloro-6-benzyloxy-7-methoxyquinazoline; 4-Chloro-7-methoxy-6-(phenylmethoxy)quinazoline; 286371-65-1; Quinazoline, 4-chloro-7-methoxy-6-(phenylmethoxy)-; 6-Benzyloxy-4-chloro-7-methoxyquinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Methoxy-6-Benzyloxyquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.