Description

2,4-Bis(Trifluoromethyl)Benzylamine is a high-value, fluorinated aromatic amine building block. This compound matters for its unique combination of a reactive primary amine group and a highly electron-deficient, lipophilic bis(trifluoromethyl)benzene core, which is critical for modulating the physicochemical properties of advanced molecules. It is primarily needed by R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, oncology, and antiviral therapies, where the trifluoromethyl groups enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved weatherfastness, bioavailability, and pest selectivity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, leveraging the steric and electronic influence of the CF3 groups.
• Advanced Material Precursor: Employed in the production of specialty polymers, liquid crystals, and organic electronic materials, where its structure aids in tuning thermal stability, solubility, and optical properties.
• Fluorinated Dye & Pigment Intermediate: Acts as a starting material for synthesizing high-performance, light-fast fluorinated dyes and pigments for specialized coatings and imaging applications.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Benzylamine
CAS No.	286010-20-6
Molecular Formula	C10H7F6N
Molecular Weight	255.16 g/mol
Synonyms	2,4-Bis(trifluoromethyl)benzenemethanamine; α,α,α,α',α',α'-Hexafluoro-2,4-xylidine; (2,4-Bis(trifluoromethyl)phenyl)methanamine; 1-(Aminomethyl)-2,4-bis(trifluoromethyl)benzene; 2,4-Bis(trifluoromethyl)benzyl amine; 286010-20-6; 2,4-Di(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Trifluoromethyl)Benzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments, supporting cGMP and ISO 9001 compliance for our pharmaceutical and industrial partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive and reacts with strong acids and bases; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.