Description

1-tert-Butyl-3-(Naphthalen-2-Ylmethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. Its molecular architecture makes it a valuable scaffold in medicinal chemistry for the research and development of novel therapeutic agents. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on kinase inhibitor programs and other targeted drug discovery applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic assays and biological target validation studies.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, functionalized pyrazolopyrimidine derivatives.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and pre-clinical development services.

Basic Information

Item	Details
Product Name	1-tert-Butyl-3-(Naphthalen-2-Ylmethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	284672-30-6
Molecular Formula	C22H25N5
Molecular Weight	359.47 g/mol
Synonyms	1-(tert-Butyl)-3-[(naphthalen-2-yl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-tert-Butyl-3-(2-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 284672-30-6; UNII-1J8K9Q9S4F; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-[(2-naphthalenyl)methyl]-; BDBM50191035; 1-tert-butyl-3-(naphthalen-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-3-(Naphthalen-2-Ylmethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.