Description

Ac-Ile-Tyr(Po3H2)-Gly-Glu-Phe-Nh2 CAS NO 284660-72-6 is a chemically synthesized, phosphorylated peptide derivative, specifically designed for advanced biochemical and pharmaceutical research. This compound is critical for studying intracellular signaling pathways, particularly those involving tyrosine phosphorylation, which is a fundamental regulatory mechanism in cell biology. It serves as an essential tool for researchers and developers in pharmaceutical discovery, proteomics, and signal transduction research, enabling the development of targeted therapies and diagnostic assays.

Application

• Biochemical Research Reagent: Used as a high-purity standard or substrate in enzymatic studies, particularly for kinases and phosphatases.
• Pharmaceutical Development: Acts as a key intermediate or reference compound in the discovery and validation of novel drug candidates targeting phosphotyrosine-mediated pathways.
• Proteomics & Diagnostics: Employed in mass spectrometry and immunoassay development for the detection and quantification of phosphorylated proteins.
• Cell Signaling Studies: Essential for in vitro and cell-based assays to investigate the role of specific phosphorylation events in cellular processes like growth, differentiation, and apoptosis.
• Antibody Production: Can be used as an antigen for generating and screening phospho-specific antibodies.

Basic Information

Item	Detail
Product Name	Ac-Ile-Tyr(Po3H2)-Gly-Glu-Phe-Nh2
CAS No.	284660-72-6
Molecular Formula	C38H53N7O14P
Molecular Weight	886.84 g/mol
Synonyms	Acetyl-Isoleucine-Tyrosine(phospho)-Glycine-Glutamic Acid-Phenylalanine amide; N-Acetyl-L-isoleucyl-O-phosphono-L-tyrosylglycyl-L-α-glutamyl-L-phenylalaninamide; Phosphotyrosine Peptide; pTyr Peptide; Ac-Ile-pTyr-Gly-Glu-Phe-NH2; Signal Transduction Peptide; Research Peptide 284660-72-6
EINECS	Contact for details

Quality Control

Every batch of our Ac-Ile-Tyr(Po3H2)-Gly-Glu-Phe-Nh2 is manufactured and analyzed under strict quality management systems. We guarantee high purity and batch-to-batch consistency through comprehensive analytical techniques including HPLC, MS, and NMR. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.