Description

3-(3,4-Dimethoxyphenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid is a specialized, high-purity building block designed for advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a protected amino acid derivative, enabling the controlled construction of complex peptide-like molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of peptides and peptidomimetics for drug discovery programs.
• API Development: Used in the research and process development of novel Active Pharmaceutical Ingredients (APIs), particularly those requiring specific chiral centers or protected functional groups.
• Bioconjugation Chemistry: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Chemical Biology Probes: Employed in the synthesis of labeled probes and molecular tools for studying biological pathways and protein interactions.
• Fine Chemical Synthesis: A versatile intermediate for the preparation of complex organic molecules in academic and industrial research settings.
• Fmoc-Protected Amino Acid Analogue: Specifically used in Fmoc-based peptide synthesis strategies, offering a protected amino acid side chain for sequential coupling.

Basic Information

Product Name	3-(3,4-Dimethoxyphenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid
CAS No.	284491-98-1
Molecular Formula	C26H25NO6
Molecular Weight	447.48 g/mol
Synonyms	Fmoc-3-(3,4-Dimethoxyphenyl)-β-alanine; Fmoc-3,4-Dimethoxy-β-homoPhe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3,4-dimethoxyphenyl)-β-alanine; 3-(3,4-Dimethoxyphenyl)-3-[(9-fluorenylmethoxycarbonyl)amino]propanoic acid; 3-[(Fmoc-amino]-3-(3,4-dimethoxyphenyl)propionic acid; Fmoc-3,4-Dimethoxy-β-phenylalanine; Fmoc-Dimethoxy-β-hPhe-OH; β-(3,4-Dimethoxyphenyl)-β-[(Fmoc)amino]propionic Acid
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dimethoxyphenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.