Description

Ethyl 4-(2-Bromophenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry and drug discovery programs. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for API development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex heterocyclic compounds and fused ring systems.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development and the exploration of new chemical reactions in academic and industrial research settings.
• Fine Chemical Production: Integrated into the manufacturing process of specialty chemicals and high-value agrochemical intermediates.

Basic Information

Product Name	Ethyl 4-(2-Bromophenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	283593-06-6
Molecular Formula	C14H15BrN2O3
Molecular Weight	339.19 g/mol
Synonyms	Ethyl 4-(2-bromophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbethoxy-4-(2-bromophenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 4-(2-Bromophenyl)-5-ethoxycarbonyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 1,2,3,4-Tetrahydropyrimidine-5-carboxylic acid, 4-(2-bromophenyl)-6-methyl-2-oxo-, ethyl ester; Biginelli Reaction Product (2-Bromophenyl derivative); DHPM derivative
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2-Bromophenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.