Description

4(3H)-Pyrimidinone, 3-Acetyl-2-(Methylthio)- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrimidinone core enables the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for lead compound optimization and process chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and antiviral agents.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Used in custom synthesis and the production of complex specialty chemicals.
• Academic & Industrial R&D: Serves as a versatile scaffold for medicinal chemistry programs and novel heterocycle exploration.
• Material Science Precursor: Potential intermediate for organic electronic materials and advanced polymers.

Basic Information

Product Name	4(3H)-Pyrimidinone, 3-Acetyl-2-(Methylthio)-
CAS No.	283168-85-4
Molecular Formula	C7H8N2O2S
Molecular Weight	184.21 g/mol
Synonyms	3-Acetyl-2-(methylthio)-4(3H)-pyrimidinone; 2-(Methylthio)-3-acetyl-4-pyrimidinol; 3-Acetyl-2-methylsulfanyl-1H-pyrimidin-4-one; 3-Acetyl-2-(methylthio)pyrimidin-4(3H)-one; 2-Methylsulfanyl-3-acetyl-4-pyrimidinol; 4-Hydroxy-2-(methylthio)-3-pyrimidinecarboxylic acid methyl ester (tautomer); 3-Acetyl-2-methylmercapto-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 4(3H)-Pyrimidinone, 3-Acetyl-2-(Methylthio)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistency and meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.