Description

Ac-Gln-Trp-Leu-NH2 CAS NO 283163-41-7 is a synthetic tetrapeptide amide derivative, featuring an N-terminal acetyl group and a C-terminal amide modification, which enhances its metabolic stability. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or a reference standard for bioactive peptide studies. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical manufacturers engaged in peptide-based drug discovery, metabolic research, and biochemical assay development.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial building block or a reference compound in the synthesis and development of novel therapeutic peptides.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and peptide metabolism pathways.
• Drug Discovery: Acts as a lead compound or a structural template for designing new molecules targeting specific receptors or enzymes.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of peptide-based products using techniques like HPLC and MS.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry, structure-activity relationships (SAR), and molecular biology.

Basic Information

Product Name	Ac-Gln-Trp-Leu-NH2
CAS No.	283163-41-7
Molecular Formula	C27H38N6O6
Molecular Weight	542.63 g/mol
Synonyms	Acetyl-Glutamine-Tryptophan-Leucine amide; N-Acetyl-L-glutaminyl-L-tryptophyl-L-leucinamide; Ac-Gln-Trp-Leu-NH2; Ac-Q-W-L-NH2; L-Leucinamide, N-acetyl-L-glutaminyl-L-tryptophyl-; Tetrapeptide amide Ac-Gln-Trp-Leu-NH2; 283163-41-7; N-Acetylglutaminyltryptophylleucinamide
EINECS	Contact for details

Quality Control

Our Ac-Gln-Trp-Leu-NH2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (or as specified on the label). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under desiccant or inert atmosphere after opening to prevent degradation. For long-term storage, consider freezing at -20°C or below.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.