Description

(S)-3-(Fmoc-Amino)Adipic Acid 6-Amide is a high-purity, chiral Fmoc-protected amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for the solid-phase and solution-phase construction of complex peptides and peptidomimetics, offering precise stereochemical control. It is essential for researchers and manufacturers in pharmaceutical development, particularly in creating therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Peptide Synthesis: A key chiral intermediate in Fmoc-based solid-phase peptide synthesis (SPPS) for the controlled incorporation of modified amino acid residues.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or reporter molecules in bioconjugation chemistry.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Proteomics Research: Utilized in the synthesis of custom peptide standards, antigens, and substrates for mass spectrometry and enzymatic studies.
• Material Science: Potential application in the synthesis of peptide-polymer hybrids and bio-inspired materials requiring specific chiral centers.

Basic Information

Product Name	(S)-3-(Fmoc-Amino)Adipic Acid 6-Amide
CAS No.	283160-17-8
Molecular Formula	C25H28N2O5
Molecular Weight	436.50 g/mol
Synonyms	Fmoc-Ada-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-aminohexanedioic acid 6-amide; (S)-3-[(Fmoc)amino]adipic acid 6-amide; 6-Amino-3-[(9H-fluoren-9-ylmethoxycarbonyl)amino]hexanoic acid amide; Fmoc-3-Ahx-NH2; Fmoc-β-homoGlu(NH2)-OH; (S)-3-(Fmoc-amino)adipamide
EINECS	Contact for details

Quality Control

Our (S)-3-(Fmoc-Amino)Adipic Acid 6-Amide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to industry best practices and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.