Description

n-((Rs)-2-Hydroxy-2-Phenyl-Ethyl)-Val-Leu-Anilide CAS NO 282732-35-8 is a specialized synthetic peptide derivative, characterized by its chiral center and anilide functional group. This compound is of significant value in pharmaceutical research and development, particularly as a key intermediate or reference standard in the synthesis of more complex bioactive molecules. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in peptide chemistry, medicinal chemistry, and the development of enzyme inhibitors or receptor modulators.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, particularly for proteases like dipeptidyl peptidase IV (DPP-IV) and other serine proteases.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of therapeutic peptides.
• Process Development: Acts as a model compound for developing and scaling up chromatographic purification and analytical methods for chiral molecules.
• Academic Research: Utilized in universities and research labs for investigating peptide synthesis methodologies, chiral resolution, and molecular recognition.

Basic Information

Product Name	n-((Rs)-2-Hydroxy-2-Phenyl-Ethyl)-Val-Leu-Anilide
CAS No.	282732-35-8
Molecular Formula	C25H33N3O3
Molecular Weight	423.55 g/mol
Synonyms	N-[(2R)-2-Hydroxy-2-phenylethyl]-L-valyl-N-(1-methylpropyl)-L-phenylalaninamide; (R)-N-(2-Hydroxy-2-phenylethyl)-Val-Leu-Phe-NH2 (anilide variant); Val-Leu-Anilide derivative; DPP-IV Inhibitor Intermediate; Peptide anilide; Chiral peptide intermediate; UNII-Not Assigned; Research Peptide 282732-35-8
EINECS	Contact for details

Quality Control

Our n-((Rs)-2-Hydroxy-2-Phenyl-Ethyl)-Val-Leu-Anilide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.