Description

Fmoc-1-Amino-Cyclohexane Acetic Acid is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block for introducing the 1-aminocyclohexane acetic acid moiety into peptide chains under standard Fmoc solid-phase peptide synthesis (SPPS) conditions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and chemical biology probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy synthesis of complex peptides.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Design: Incorporates the constrained cyclohexyl structure to modulate peptide conformation, stability, and biological activity.
• Chemical Biology & Proteomics: Employed in the synthesis of labeled peptides, activity-based probes, and protein interaction studies.
• Combinatorial Chemistry: A valuable building block for generating diverse peptide libraries for screening.
• Academic & Industrial Research: Supports fundamental research in medicinal chemistry, biochemistry, and material science.

Basic Information

Product Name	Fmoc-1-Amino-Cyclohexane Acetic Acid
CAS No.	282524-98-5
Molecular Formula	C23H25NO4
Molecular Weight	379.45 g/mol
Synonyms	Fmoc-Ac6c-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-aminocyclohexaneacetic acid; 1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclohexaneacetic acid; Fmoc-1-Aminocyclohexylacetic Acid; Fmoc-Ac6c; (1-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclohexane-1-acetic acid
EINECS	Contact for details

Quality Control

Our Fmoc-1-Amino-Cyclohexane Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for peptide synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing consistent quality, lot-to-lot traceability, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.