Description

Cyclohexanecarboxylic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci) is a specialized Fmoc-protected amino acid derivative, a critical building block in modern organic synthesis. This compound is essential for the controlled assembly of complex molecules, offering precise stereochemistry and functional group compatibility. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and other bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential addition of amino acids, particularly those with cyclohexyl side chains, to construct target peptide sequences.
• Pharmaceutical Research & Development: Serves as a crucial building block in medicinal chemistry for creating libraries of novel drug candidates, especially in metabolic disease and oncology research.
• Peptidomimetic Design: Used to synthesize non-natural peptide analogs with enhanced stability, bioavailability, and target specificity for therapeutic applications.
• Bioconjugation and Probe Development: Facilitates the site-specific labeling of peptides and proteins with tags, dyes, or other functional molecules for diagnostic and biochemical studies.
• Academic Organic Synthesis: Employed in research laboratories for methodological development and the synthesis of complex natural products or chiral auxiliaries.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci)
CAS No.	282524-96-3
Molecular Formula	C22H23NO4
Molecular Weight	365.42 g/mol
Synonyms	Fmoc-2-Aminocyclohexanecarboxylic Acid; Fmoc-Cyh-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-aminocyclohexanecarboxylic acid; 2-[(Fmoc-amino)cyclohexanecarboxylic acid; (1R,2S)-rel-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclohexanecarboxylic acid; Fmoc-Achc-OH; Fmoc-2-Amino-cyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We support compliance with research and cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.