Description

H-Thr-Pro-Oh is a high-purity, protected dipeptide building block essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise molecular control in the development of novel therapeutic peptides and biochemical probes. It serves as a key intermediate for pharmaceutical R&D, particularly in the creation of peptide-based drugs targeting metabolic and neurological pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the solid-phase and solution-phase synthesis of complex therapeutic peptides.
• Biochemical Research: Used in proteomics and enzymology studies to investigate enzyme-substrate interactions and protein folding mechanisms.
• Drug Discovery: Serves as a scaffold or precursor in medicinal chemistry for developing new drug candidates with improved stability and bioavailability.
• Peptide Library Construction: Enables the generation of diverse peptide libraries for high-throughput screening in identifying bioactive compounds.
• API Synthesis: Employed in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for clinical trial materials and commercial production.
• Cosmeceutical Development: Used in the research and formulation of advanced bioactive peptides for skincare and anti-aging products.

Basic Information

Product Name	H-Thr-Pro-Oh
CAS No.	281670-51-7
Molecular Formula	C8H14N2O4
Molecular Weight	202.21 g/mol
Synonyms	H-Thr-Pro-OH; L-Threonyl-L-proline; Thr-Pro; T-P; (2S,3R)-2-((S)-Pyrrolidine-2-carboxamido)-3-hydroxybutanoic acid; Fmoc-Thr(tBu)-Pro-OH (precursor); Boc-Thr(Bzl)-Pro-OH (precursor); Protected Thr-Pro dipeptide
EINECS	Contact for details

Quality Control

Our H-Thr-Pro-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to stringent in-process controls and final release testing protocols to meet the exacting standards of the pharmaceutical and biotechnology industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.