Description

1H-Imidazole-2-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the imidazole-2-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of potential drug candidates, especially those targeting enzymes where the imidazole-sulfonamide pharmacophore is relevant.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require sulfonamide functional groups.
• Material Science: Building block for creating specialized polymers, ligands, or metal-organic frameworks (MOFs) with unique properties.
• Bioconjugation Chemistry: Employed to modify proteins, peptides, or other biomolecules by sulfonylation of amino groups.
• Chemical Research: A valuable tool for academic and industrial R&D in exploring new synthetic methodologies and creating compound libraries for screening.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex colorants and functional dyes.

Basic Information

Product Name	1H-Imidazole-2-Sulfonyl Chloride
CAS No.	281221-70-3
Molecular Formula	C3H3ClN2O2S
Molecular Weight	166.58 g/mol
Synonyms	Imidazole-2-sulfonyl chloride; 2-Imidazolesulfonyl chloride; 1H-Imidazole-2-sulfonyl chloride; 2-(Chlorosulfonyl)-1H-imidazole; 1H-Imidazole-2-sulfonchlorid; 2-Sulfonyl chloride imidazole
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-2-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.