Description

2,5-Dichloro-n-(4-Fluorophenyl)Pyrimidin-4-Amine is a high-purity, fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogenated structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce novel functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated pyrimidine core.
• Material Science Research: Serves as a precursor for creating functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific halogenated aromatic amines.
• Academic & Industrial R&D: Used in exploratory chemistry for developing new synthetic methodologies and discovering novel compounds.

Basic Information

Product Name	2,5-Dichloro-n-(4-Fluorophenyl)Pyrimidin-4-Amine
CAS No.	280582-13-0
Molecular Formula	C10H6Cl2FN3
Molecular Weight	258.08 g/mol
Synonyms	4-Amino-2,5-dichloro-N-(4-fluorophenyl)pyrimidine; 2,5-Dichloro-4-[(4-fluorophenyl)amino]pyrimidine; 2,5-Dichloro-N-(4-fluorophenyl)pyrimidin-4-amine; 4-Pyrimidinamine, 2,5-dichloro-N-(4-fluorophenyl)-; N-(4-Fluorophenyl)-2,5-dichloropyrimidin-4-amine; 280582-13-0; 2,5-Dichloro-4-(4-fluoroanilino)pyrimidine
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-n-(4-Fluorophenyl)Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.