Description

(2-Chloro-5-Fluoro-Pyrimidin-4-Yl)-Phenyl-Amine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in academic and industrial R&D.
• Material Science Research: Potential precursor for the development of organic electronic materials and specialty polymers.
• Bioconjugation & Probe Synthesis: Utilized in medicinal chemistry for creating labeled compounds and biochemical probes.

Basic Information

Product Name	(2-Chloro-5-Fluoro-Pyrimidin-4-Yl)-Phenyl-Amine
CAS No.	280581-64-8
Molecular Formula	C10H7ClFN3
Molecular Weight	223.64 g/mol
Synonyms	4-Anilino-2-chloro-5-fluoropyrimidine; N-(2-Chloro-5-fluoropyrimidin-4-yl)aniline; 2-Chloro-5-fluoro-N-phenylpyrimidin-4-amine; 4-(Phenylamino)-2-chloro-5-fluoropyrimidine; 280581-64-8; (2-Chloro-5-fluoropyrimidin-4-yl)phenylamine; Aniline, N-(2-chloro-5-fluoropyrimidin-4-yl)-
EINECS	Contact for details

Quality Control

Our (2-Chloro-5-Fluoro-Pyrimidin-4-Yl)-Phenyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.