Description

5-Bromo-2-Chloro-n-Phenyl-4-Pyrimidinamine CAS NO 280581-50-2 is a high-purity pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its functionalized structure, which serves as a versatile intermediate for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyrimidine core.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic libraries for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of target molecules under cGMP or other quality frameworks.

Basic Information

Product Name	5-Bromo-2-Chloro-n-Phenyl-4-Pyrimidinamine
CAS No.	280581-50-2
Molecular Formula	C10H7BrClN3
Molecular Weight	284.54 g/mol
Synonyms	5-Bromo-2-chloro-N-phenylpyrimidin-4-amine; 4-Pyrimidinamine, 5-bromo-2-chloro-N-phenyl-; 5-Bromo-2-chloro-4-(phenylamino)pyrimidine; 2-Chloro-5-bromo-N-phenyl-4-pyrimidinamine; 280581-50-2; 5-Bromo-2-chloro-4-anilinopyrimidine; 4-Amino-5-bromo-2-chloro-N-phenylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-n-Phenyl-4-Pyrimidinamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems support the needs of research and development, with the capability to supply material meeting specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.