Description

1-(3',4'-Difluorophenyl)Ethylamine is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with enhanced biological or physical properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the difluorophenyl moiety can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, critical for producing enantiomerically pure compounds.
• Advanced Material Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic units.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	1-(3',4'-Difluorophenyl)Ethylamine
CAS No.	276875-21-9
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	1-(3,4-Difluorophenyl)ethanamine; α-Methyl-3,4-difluorobenzeneethanamine; (1-(3,4-Difluorophenyl)ethyl)amine; 3,4-Difluoro-α-methylbenzylamine; 1-(3,4-Difluorophenyl)ethylamine; (R/S)-1-(3,4-Difluorophenyl)ethylamine; Benzenemethanamine, α-methyl-3,4-difluoro-
EINECS	Contact for details

Quality Control

Our 1-(3',4'-Difluorophenyl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details (R/S or enantiopure grades available)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.