Description

(3Ar,4S,6R,6As)-6-[7-Amino-5-(Propylthio)-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-3-Yl]Tetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-Ol is a high-purity, complex nucleoside analog derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a critical intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel antiviral and anticancer therapeutics. It is specifically engineered for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of nucleoside-based antiviral drugs.
• Antiviral Drug Research: Investigated for its potential activity against a range of viral targets due to its modified nucleoside structure.
• Oncology Research: Used in the discovery and synthesis of potential chemotherapeutic agents targeting DNA/RNA synthesis.
• Biochemical Tool Compound: Employed in enzymatic studies and as a probe to understand nucleoside metabolism and related pathways.
• Process Chemistry & Scale-up: Utilized in route development and optimization for the commercial manufacturing of complex APIs.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specialized nucleoside chemistry.

Basic Information

Product Name	(3Ar,4S,6R,6As)-6-[7-Amino-5-(Propylthio)-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-3-Yl]Tetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-Ol
CAS No.	274693-22-0
Molecular Formula	C15H22N6O3S
Molecular Weight	366.44 g/mol
Synonyms	6-[7-Amino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol; 1,2,3-Triazolo[4,5-d]pyrimidine nucleoside derivative; 274693-22-0; (3aR,4S,6R,6aR)-6-[7-Amino-5-(propylsulfanyl)-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-ol; Propylthio-triazolopyrimidine nucleoside
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development under cGMP conditions where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.