Description

H-D-Lys(Alloc)-Oh CAS NO 274260-42-3 is a protected derivative of the essential amino acid L-lysine, featuring an Alloc (allyloxycarbonyl) protecting group on the side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with orthogonal side-chain protection.
• Pharmaceutical Research: Used in the R&D of peptide-based drugs, including hormones, antimicrobial peptides, and targeted therapeutics.
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Biochemical Tool Development: Used to synthesize labeled or modified peptides for use as probes, substrates, or standards in assays.
• Academic Research: Fundamental research tool in universities and institutes studying protein structure, function, and interactions.

Basic Information

Product Name	H-D-Lys(Alloc)-Oh
CAS No.	274260-42-3
Molecular Formula	C10H18N2O4
Molecular Weight	230.26 g/mol
Synonyms	D-Lysine, N6-[(allyloxy)carbonyl]-; N-Alloc-D-lysine; (R)-2-Amino-6-((allyloxycarbonyl)amino)hexanoic acid; Fmoc-D-Lys(Alloc)-OH (precursor); Alloc-D-Lys-OH; D-Lys(Alloc); Boc-D-Lys(Alloc)-OH (related derivative); Nε-Alloc-D-lysine
EINECS	Contact for details

Quality Control

Our H-D-Lys(Alloc)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.