Description

Phenol, 5-Amino-4-Chloro-2-Fluoro- is a halogenated and aminated phenol derivative, serving as a critical multifunctional building block in advanced organic synthesis. Its unique substitution pattern provides a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antibiotics, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, leveraging its halogenated phenol core for bioactivity.
• Dye and Pigment Manufacturing: Serves as a starting material for producing specialized azo dyes and high-performance pigments.
• Material Science: Employed in the synthesis of monomers for specialty polymers, resins, and advanced functional materials.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Liquid Crystal and Electronic Chemicals: Potential use in the synthesis of intermediates for liquid crystal displays (LCDs) and other electronic applications.

Basic Information

Product Name	Phenol, 5-Amino-4-Chloro-2-Fluoro-
CAS No.	270899-93-9
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	5-Amino-4-chloro-2-fluorophenol; 4-Chloro-2-fluoro-5-aminophenol; 2-Fluoro-5-amino-4-chlorophenol; 4-Chloro-5-amino-2-fluorophenol; 2-Fluoro-4-chloro-5-aminophenol; 5-Amino-4-chloro-2-fluorophenol; 4-Chloro-2-fluoro-5-hydroxyaniline; 2-Fluoro-4-chloro-5-hydroxyaniline
EINECS	Contact for details

Quality Control

Our Phenol, 5-Amino-4-Chloro-2-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.