Description

1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[(4Ar,7Ar)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial importance for its critical role in the synthesis of novel antibacterial agents. It is primarily required by pharmaceutical R&D departments and active pharmaceutical ingredient (API) manufacturers engaged in the development of next-generation quinolone antibiotics.

Application

• Key Intermediate for Antibacterial APIs: Serves as a crucial building block in the synthesis of advanced fluoroquinolone antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material and commercial API batches.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) specializing in complex molecule synthesis.

Basic Information

Product Name	1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[(4Ar,7Ar)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	268545-13-7
Molecular Formula	C21H24FN3O4
Molecular Weight	401.43 g/mol
Synonyms	7-[(4aR,7aR)-Octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid; (4aR,7aR)-7-(Octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid; Garenoxacin Intermediate; Garenoxacin Related Compound; Quinolonecarboxylic Acid Derivative; Antibacterial Intermediate; 268545-13-7
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[(4Ar,7Ar)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.