Description

(S)-n-4-Fmoc-n-8-Boc-Diaminooctanoic Acid CAS NO 268542-17-2 is a high-purity, orthogonally protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for constructing complex peptides and peptidomimetics with precise stereochemistry and side-chain functionality. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, protein engineering, and chemical biology studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of peptides, particularly those requiring specific side-chain modifications.
• Peptidomimetic Drug Discovery: Used to synthesize non-natural peptide analogs with enhanced stability, bioavailability, and target affinity for therapeutic applications.
• Chemical Biology Probes: Enables the site-specific incorporation of functional handles or labels into peptides for studying protein-protein interactions and cellular processes.
• Linker and Conjugation Chemistry: Serves as a versatile spacer or functionalized linker in the synthesis of peptide-drug conjugates (PDCs) and bioconjugates.
• Custom Peptide Services: An essential raw material for CROs and CDMOs offering bespoke peptide manufacturing for research and pre-clinical development.

Basic Information

Item	Detail
Product Name	(S)-n-4-Fmoc-n-8-Boc-Diaminooctanoic Acid
CAS No.	268542-17-2
Molecular Formula	C28H36N2O6
Molecular Weight	496.60 g/mol
Synonyms	Fmoc-Lys(Boc)-OH; Nα-Fmoc-Nε-Boc-L-lysine; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; Fmoc-Lys(Boc)-OH; Nα-Fmoc-Nε-Boc-L-lysine; Fmoc-Lys(Boc); Boc-Lys(Fmoc)-OH; N-ε-Boc-N-α-Fmoc-L-lysine
EINECS	Contact for details

Quality Control

Every batch of (S)-n-4-Fmoc-n-8-Boc-Diaminooctanoic Acid is manufactured under strict quality management systems. We guarantee high chemical purity and chiral integrity, supported by comprehensive analytical testing including HPLC, NMR, and optical rotation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.