Description

4-Ethoxy-3-(1-Methyl-7-Oxo-3-Propyl-6,7-Dihydro-1H-Pyrazolo[4,3-D]Pyrimidin-5-Yl)-n-Phenylbenzenesulfonamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for targeting specific enzymatic pathways. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents. Its precise molecular architecture makes it a valuable building block for creating potential drug candidates with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• Enzyme Inhibitor Development: Investigated for its potential in creating selective inhibitors, given its pyrazolopyrimidine sulfonamide structure common in kinase and phosphodiesterase (PDE) inhibitor research.
• Preclinical Candidate Synthesis: Employed in the multistep synthesis of compounds for preclinical evaluation and lead optimization.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	4-Ethoxy-3-(1-Methyl-7-Oxo-3-Propyl-6,7-Dihydro-1H-Pyrazolo[4,3-D]Pyrimidin-5-Yl)-n-Phenylbenzenesulfonamide
CAS No.	268203-51-6
Molecular Formula	C23H25N5O4S
Molecular Weight	467.54 g/mol
Synonyms	4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-phenylbenzenesulfonamide; Tadalafil Impurity; Tadalafil Related Compound; PDE5 Inhibitor Intermediate; 1H-Pyrazolo[4,3-d]pyrimidin-5-ylbenzenesulfonamide derivative; 268203-51-6; UNII-9K5N8V5T2I
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-(1-Methyl-7-Oxo-3-Propyl-6,7-Dihydro-1H-Pyrazolo[4,3-D]Pyrimidin-5-Yl)-n-Phenylbenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.