Description

5-Amino-2-(Phenoxy)Benzotrifluoride is a high-value trifluoromethyl-substituted aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both an amino group and a phenoxy linkage, makes it an essential intermediate for creating complex, functional molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing high-performance, light-fast dyes and functional pigments.
• Liquid Crystal & OLED Development: Building block for synthesizing fluorinated compounds used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex biaryl ether structures.

Basic Information

Product Name	5-Amino-2-(Phenoxy)Benzotrifluoride
CAS No.	267416-81-9
Molecular Formula	C₁₃H₁₀F₃NO
Molecular Weight	253.22 g/mol
Synonyms	2-Phenoxy-5-(trifluoromethyl)aniline; 5-Amino-2-phenoxybenzotrifluoride; 2-Phenoxy-α,α,α-trifluoro-p-toluidine; 5-(Trifluoromethyl)-2-phenoxyaniline; Benzenamine, 2-phenoxy-5-(trifluoromethyl)-; [2-Phenoxy-5-(trifluoromethyl)phenyl]amine
EINECS	Contact for details

Quality Control

Our 5-Amino-2-(Phenoxy)Benzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.