Description

5-(2-Chloro-6-Methylpyrimidin-4-Yl)-4-(4-Chlorophenyl)-4H-1,2,4-Triazole-3-Thiol is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially for antiviral, anticancer, or central nervous system (CNS) targeted therapies.
• Agrochemical Research: Serves as a core scaffold for developing new fungicides, herbicides, or insecticides with novel modes of action.
• Chemical Biology Probe: Used in medicinal chemistry and drug discovery programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Material Science Research: Potential building block for creating novel organic electronic materials or ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Item	Detail
Product Name	5-(2-Chloro-6-Methylpyrimidin-4-Yl)-4-(4-Chlorophenyl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	266337-73-9
Molecular Formula	C13H9Cl2N5S
Molecular Weight	338.21 g/mol
Synonyms	4-(4-Chlorophenyl)-5-(2-chloro-6-methyl-4-pyrimidinyl)-4H-1,2,4-triazole-3-thiol; 5-(2-Chloro-6-methylpyrimidin-4-yl)-4-(4-chlorophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 4-(4-Chlorophenyl)-5-(2-chloro-6-methylpyrimidin-4-yl)-4H-1,2,4-triazole-3-thiol; 266337-73-9; 5-(2-Chloro-6-methyl-4-pyrimidinyl)-4-(4-chlorophenyl)-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 5-(2-Chloro-6-Methylpyrimidin-4-Yl)-4-(4-Chlorophenyl)-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.